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The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly

We have identified Talpid3/KIAA0586 as a component of a CP110-containing protein complex important for centrosome and cilia function. Talpid3 assembles a ring-like structure at the extreme distal end of centrioles. Ablation of Talpid3 resulted in an aberrant distribution of centriolar satellites inv...

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Detalles Bibliográficos
Autores principales: Kobayashi, Tetsuo, Kim, Sehyun, Lin, Yu-Chun, Inoue, Takanari, Dynlacht, Brian David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897186/
https://www.ncbi.nlm.nih.gov/pubmed/24421332
http://dx.doi.org/10.1083/jcb.201304153