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The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly
We have identified Talpid3/KIAA0586 as a component of a CP110-containing protein complex important for centrosome and cilia function. Talpid3 assembles a ring-like structure at the extreme distal end of centrioles. Ablation of Talpid3 resulted in an aberrant distribution of centriolar satellites inv...
Autores principales: | Kobayashi, Tetsuo, Kim, Sehyun, Lin, Yu-Chun, Inoue, Takanari, Dynlacht, Brian David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897186/ https://www.ncbi.nlm.nih.gov/pubmed/24421332 http://dx.doi.org/10.1083/jcb.201304153 |
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