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DNA replication and spindle checkpoints cooperate during S phase to delay mitosis and preserve genome integrity
Deoxyribonucleic acid (DNA) replication and chromosome segregation must occur in ordered sequence to maintain genome integrity during cell proliferation. Checkpoint mechanisms delay mitosis when DNA is damaged or upon replication stress, but little is known on the coupling of S and M phases in unper...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897190/ https://www.ncbi.nlm.nih.gov/pubmed/24421333 http://dx.doi.org/10.1083/jcb.201306023 |