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DNA replication and spindle checkpoints cooperate during S phase to delay mitosis and preserve genome integrity

Deoxyribonucleic acid (DNA) replication and chromosome segregation must occur in ordered sequence to maintain genome integrity during cell proliferation. Checkpoint mechanisms delay mitosis when DNA is damaged or upon replication stress, but little is known on the coupling of S and M phases in unper...

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Detalles Bibliográficos
Autores principales: Magiera, Maria M., Gueydon, Elisabeth, Schwob, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897190/
https://www.ncbi.nlm.nih.gov/pubmed/24421333
http://dx.doi.org/10.1083/jcb.201306023