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SIV Vpx Is Essential for Macrophage Infection but Not for Development of AIDS

Analysis of rhesus macaques infected with a vpx deletion mutant virus of simian immunodeficiency virus mac239 (SIVΔvpx) demonstrates that Vpx is essential for efficient monocyte/macrophage infection in vivo but is not necessary for development of AIDS. To compare myeloid-lineage cell infection in mo...

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Detalles Bibliográficos
Autores principales: Westmoreland, Susan V., Converse, A. Peter, Hrecka, Kasia, Hurley, Mollie, Knight, Heather, Piatak, Michael, Lifson, Jeffrey, Mansfield, Keith G., Skowronski, Jacek, Desrosiers, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897363/
https://www.ncbi.nlm.nih.gov/pubmed/24465411
http://dx.doi.org/10.1371/journal.pone.0084463