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SIV Vpx Is Essential for Macrophage Infection but Not for Development of AIDS

Analysis of rhesus macaques infected with a vpx deletion mutant virus of simian immunodeficiency virus mac239 (SIVΔvpx) demonstrates that Vpx is essential for efficient monocyte/macrophage infection in vivo but is not necessary for development of AIDS. To compare myeloid-lineage cell infection in mo...

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Detalles Bibliográficos
Autores principales:	Westmoreland, Susan V., Converse, A. Peter, Hrecka, Kasia, Hurley, Mollie, Knight, Heather, Piatak, Michael, Lifson, Jeffrey, Mansfield, Keith G., Skowronski, Jacek, Desrosiers, Ronald C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897363/ https://www.ncbi.nlm.nih.gov/pubmed/24465411 http://dx.doi.org/10.1371/journal.pone.0084463

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