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Autophagy Inhibition Contributes to the Synergistic Interaction between EGCG and Doxorubicin to Kill the Hepatoma Hep3B Cells

(-)-Epigallocatechin-3-O-gallate(EGCG), the highest catechins from green tea, has promisingly been found to sensitize the efficacy of several chemotherapy agents like doxorubicin (DOX) in hepatocellular carcinoma (HCC) treatment. However, the detailed mechanisms by which EGCG augments the chemothera...

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Detalles Bibliográficos
Autores principales: Chen, Li, Ye, Hui-Lan, Zhang, Guo, Yao, Wen-Min, Chen, Xing-Zhou, Zhang, Fa-Can, Liang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897495/
https://www.ncbi.nlm.nih.gov/pubmed/24465696
http://dx.doi.org/10.1371/journal.pone.0085771