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Rapid and Unambiguous Detection of DNase I Hypersensitive Site in Rare Population of Cells
DNase I hypersensitive (DHS) sites are important for understanding cis regulation of gene expression. However, existing methods for detecting DHS sites in small numbers of cells can lead to ambiguous results. Here we describe a simple new method, in which DNA fragments with ends generated by DNase I...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897510/ https://www.ncbi.nlm.nih.gov/pubmed/24465674 http://dx.doi.org/10.1371/journal.pone.0085740 |