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Signal Intensities Derived from Different NMR Probes and Parameters Contribute to Variations in Quantification of Metabolites

We discovered that serious issues could arise that may complicate interpretation of metabolomic data when identical samples are analyzed at more than one NMR facility, or using slightly different NMR parameters on the same instrument. This is important because cross-center validation metabolomics st...

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Detalles Bibliográficos
Autores principales: Lacy, Paige, McKay, Ryan T., Finkel, Michael, Karnovsky, Alla, Woehler, Scott, Lewis, Michael J., Chang, David, Stringer, Kathleen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897511/
https://www.ncbi.nlm.nih.gov/pubmed/24465670
http://dx.doi.org/10.1371/journal.pone.0085732