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Mechanisms of Ghrelin Anti-Heart Failure: Inhibition of Ang II-Induced Cardiomyocyte Apoptosis by Down-Regulating AT1R Expression

BACKGROUND: Ghrelin is a novel growth hormone–releasing peptide administered to treat chronic heart failure (CHF). However, the underlying mechanism of its protective effects against heart failure (HF) remains unclear. METHODS AND RESULTS: A total of 68 patients with CHF and 20 healthy individuals w...

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Detalles Bibliográficos
Autores principales: Yang, Chunyan, Liu, Zhonghui, Liu, Kai, Yang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897516/
https://www.ncbi.nlm.nih.gov/pubmed/24465706
http://dx.doi.org/10.1371/journal.pone.0085785