Binding Mode Analyses and Pharmacophore Model Development for Stilbene Derivatives as a Novel and Competitive Class of α-Glucosidase Inhibitors

Stilbene urea derivatives as a novel and competitive class of non-glycosidic α-glucosidase inhibitors are effective for the treatment of type II diabetes and obesity. The main purposes of our molecular modeling study are to explore the most suitable binding poses of stilbene derivatives with analyzi...

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Detalles Bibliográficos
Autores principales: Lee, Yuno, Kim, Songmi, Kim, Jun Young, Arooj, Mahreen, Kim, Siu, Hwang, Swan, Kim, Byeong-Woo, Park, Ki Hun, Lee, Keun Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897524/
https://www.ncbi.nlm.nih.gov/pubmed/24465730
http://dx.doi.org/10.1371/journal.pone.0085827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897524/
https://www.ncbi.nlm.nih.gov/pubmed/24465730
http://dx.doi.org/10.1371/journal.pone.0085827

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