Cargando…

Angiopoietin-Like 4 Confers Resistance to Hypoxia/Serum Deprivation-Induced Apoptosis through PI3K/Akt and ERK1/2 Signaling Pathways in Mesenchymal Stem Cells

Angiopoietin-like 4 (ANGPTL4) is a potential anti-apoptotic agent for various cells. We examined the protective effect of ANGPTL4 on hypoxia/serum deprivation (SD)-induced apoptosis of MSCs, as well as the possible mechanisms. MSCs were obtained from rat bone marrow and cultured in vitro. Apoptosis...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Meng, Cui, Jinjin, Liu, Jingjin, Liu, Fang, Jiang, Rui, Liu, Kai, Wang, Yongshun, Yin, Li, Liu, Wenhua, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897528/
https://www.ncbi.nlm.nih.gov/pubmed/24465718
http://dx.doi.org/10.1371/journal.pone.0085808