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Effect of Sfrp5 on Cytokine Release and Insulin Action in Primary Human Adipocytes and Skeletal Muscle Cells

Secreted frizzled-related protein 5 (Sfrp5) is an adipokine with anti-inflammatory and insulin-sensitizing properties in mice. However, the mechanism of Sfrp5 action, especially in humans, is largely unknown. Therefore, cytokine release and insulin signaling were analyzed to investigate the impact o...

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Detalles Bibliográficos
Autores principales: Carstensen, Maren, Wiza, Claudia, Röhrig, Karin, Fahlbusch, Pia, Roden, Michael, Herder, Christian, Ouwens, D. Margriet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897555/
https://www.ncbi.nlm.nih.gov/pubmed/24465779
http://dx.doi.org/10.1371/journal.pone.0085906