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Reduction of Advanced-Glycation End Products Levels and Inhibition of RAGE Signaling Decreases Rat Vascular Calcification Induced by Diabetes

Advanced-glycation end products (AGEs) were recently implicated in vascular calcification, through a process mediated by RAGE (receptor for AGEs). Although a correlation between AGEs levels and vascular calcification was established, there is no evidence that reducing in vivo AGEs deposition or inhi...

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Detalles Bibliográficos
Autores principales: Brodeur, Mathieu R., Bouvet, Céline, Bouchard, Sonia, Moreau, Simon, Leblond, Jeanne, deBlois, Denis, Moreau, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897559/
https://www.ncbi.nlm.nih.gov/pubmed/24465790
http://dx.doi.org/10.1371/journal.pone.0085922