Crystallographic and Biochemical Analysis of the Mouse Poly(ADP-Ribose) Glycohydrolase

Protein poly(ADP-ribosyl)ation (PARylation) regulates a number of important cellular processes. Poly(ADP-ribose) glycohydrolase (PARG) is the primary enzyme responsible for hydrolyzing the poly(ADP-ribose) (PAR) polymer in vivo. Here we report crystal structures of the mouse PARG (mPARG) catalytic d...

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Detalles Bibliográficos
Autores principales: Wang, Zhizhi, Gagné, Jean-Philippe, Poirier, Guy G., Xu, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897571/
https://www.ncbi.nlm.nih.gov/pubmed/24465839
http://dx.doi.org/10.1371/journal.pone.0086010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897571/
https://www.ncbi.nlm.nih.gov/pubmed/24465839
http://dx.doi.org/10.1371/journal.pone.0086010

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