Cargando…

Oral Delivery of Exenatide via Microspheres Prepared by Cross-Linking of Alginate and Hyaluronate

Exenatide is an FDA-approved glucose-lowering peptide drug for the treatment of type 2 diabetes by subcutaneous injection. To address the issues on the inconvenience for patient use and the difficulty of oral administration of peptide drugs, chemical cross-linking of two pH-responsive biomaterials,...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Baojie, He, Dongyang, Fan, Yu, Liu, Nan, Chen, Yijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897602/
https://www.ncbi.nlm.nih.gov/pubmed/24465870
http://dx.doi.org/10.1371/journal.pone.0086064