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Microarray Analysis of Rat Pancreas Reveals Altered Expression of Alox15 and Regenerating Islet-Derived Genes in Response to Iron Deficiency and Overload

It is well known that iron overload can result in pancreatic iron deposition, beta-cell destruction, and diabetes in humans. Recent studies in animals have extended the link between iron status and pancreatic function by showing that iron depletion confers protection against beta-cell dysfunction an...

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Detalles Bibliográficos
Autores principales: Coffey, Richard, Nam, Hyeyoung, Knutson, Mitchell D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897611/
https://www.ncbi.nlm.nih.gov/pubmed/24465846
http://dx.doi.org/10.1371/journal.pone.0086019