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Growth Arrest Specific 2 Is Up-Regulated in Chronic Myeloid Leukemia Cells and Required for Their Growth

Although the generation of BCR-ABL is the molecular hallmark of chronic myeloid leukemia (CML), the comprehensive molecular mechanisms of the disease remain unclear yet. Growth arrest specific 2 (GAS2) regulates multiple cellular functions including cell cycle, apoptosis and calpain activities. In t...

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Detalles Bibliográficos
Autores principales: Zhou, Haixia, Ge, Yue, Sun, Lili, Ma, Wenjuan, Wu, Jie, Zhang, Xiuyan, Hu, Xiaohui, Eaves, Connie J., Wu, Depei, Zhao, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897655/
https://www.ncbi.nlm.nih.gov/pubmed/24465953
http://dx.doi.org/10.1371/journal.pone.0086195