On the Heat Stability of Amyloid-Based Biological Activity: Insights from Thermal Degradation of Insulin Fibrils

Formation of amyloid fibrils in vivo has been linked to disorders such as Alzheimer’s disease and prion-associated transmissible spongiform encephalopathies. One of the characteristic features of amyloid fibrils is the high thermodynamic stability relative both to native and disordered states which...

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Detalles Bibliográficos
Autores principales: Surmacz-Chwedoruk, Weronika, Malka, Iwona, Bożycki, Łukasz, Nieznańska, Hanna, Dzwolak, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897677/
https://www.ncbi.nlm.nih.gov/pubmed/24466022
http://dx.doi.org/10.1371/journal.pone.0086320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897677/
https://www.ncbi.nlm.nih.gov/pubmed/24466022
http://dx.doi.org/10.1371/journal.pone.0086320

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