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Reduced Peripheral Expression of the Glucocorticoid Receptor α Isoform in Individuals with Posttraumatic Stress Disorder: A Cumulative Effect of Trauma Burden

BACKGROUND: Posttraumatic stress disorder (PTSD) is a serious psychiatric condition that was found to be associated with altered functioning of the hypothalamic-pituitary-adrenal (HPA) axis and changes in glucocorticoid (GC) responsiveness. The physiological actions of GCs are primarily mediated thr...

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Detalles Bibliográficos
Autores principales: Gola, Hannah, Engler, Andrea, Morath, Julia, Adenauer, Hannah, Elbert, Thomas, Kolassa, Iris-Tatjana, Engler, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897679/
https://www.ncbi.nlm.nih.gov/pubmed/24466032
http://dx.doi.org/10.1371/journal.pone.0086333