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LRRK2 as a Potential Genetic Modifier of Synucleinopathies: Interlacing the Two Major Genetic Factors of Parkinson's Disease

Parkinson's disease (PD) and related Lewy body diseases are characterized by deposition of α-synuclein aggregates in both the central nervous system and peripheral nervous system. Synucleinopathy lesions spread to larger brain areas as the disease progresses, and prion-like cell-to-cell transmi...

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Detalles Bibliográficos
Autores principales: Hyun, Cheol Hwan, Yoon, Chae Young, Lee, He-Jin, Lee, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897686/
https://www.ncbi.nlm.nih.gov/pubmed/24465140
http://dx.doi.org/10.5607/en.2013.22.4.249