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HMGB1-Binding Heptamer Confers Anti-Inflammatory Effects in Primary Microglia Culture

High mobility group box 1 (HMGB1) is an endogenous danger signal molecule. In the postischemic brain, HMGB1 is massively released during NMDA-induced acute damage and triggers inflammatory processes. In a previous study, we demonstrated that intranasally delivered HMGB1 binding heptamer peptide (HBH...

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Detalles Bibliográficos
Autores principales: Kim, Il-Doo, Lee, Ja-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897691/
https://www.ncbi.nlm.nih.gov/pubmed/24465145
http://dx.doi.org/10.5607/en.2013.22.4.301