Cargando…

Beta-Catenin Is Vital for the Integrity of Mouse Embryonic Stem Cells

β-catenin mediated Wnt-signaling is assumed to play a major function in embryonic stem cells in maintaining their stem cell character and the exit from this unique trait. The complexity of β-catenin action and conflicting results on the role of β-catenin in maintaining the pluripotent state have mad...

Descripción completa

Detalles Bibliográficos
Autores principales: Raggioli, Angelo, Junghans, Dirk, Rudloff, Stefan, Kemler, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897734/
https://www.ncbi.nlm.nih.gov/pubmed/24466203
http://dx.doi.org/10.1371/journal.pone.0086691