Comparison of CpG Island Methylator Phenotype (CIMP) Frequency in Colon Cancer Using Different Probe- and Gene-Specific Scoring Alternatives on Recommended Multi-Gene Panels

BACKGROUND: In colorectal cancer a distinct subgroup of tumours demonstrate the CpG island methylator phenotype (CIMP). However, a consensus of how to score CIMP is not reached, and variation in definition may influence the reported CIMP prevalence in tumours. Thus, we sought to compare currently su...

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Detalles Bibliográficos
Autores principales: Berg, Marianne, Hagland, Hanne R., Søreide, Kjetil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897740/
https://www.ncbi.nlm.nih.gov/pubmed/24466191
http://dx.doi.org/10.1371/journal.pone.0086657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897740/
https://www.ncbi.nlm.nih.gov/pubmed/24466191
http://dx.doi.org/10.1371/journal.pone.0086657

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