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ArchiLD: Hierarchical Visualization of Linkage Disequilibrium in Human Populations

Linkage disequilibrium (LD) is an essential metric for selecting single-nucleotide polymorphisms (SNPs) to use in genetic studies and identifying causal variants from significant tag SNPs. The explosion in the number of polymorphisms that can now be genotyped by commercial arrays makes the interpret...

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Detalles Bibliográficos
Autores principales: Melchiotti, Rossella, Rötzschke, Olaf, Poidinger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897757/
https://www.ncbi.nlm.nih.gov/pubmed/24466224
http://dx.doi.org/10.1371/journal.pone.0086761