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Genetic Variations of ABCC2 Gene Associated with Adverse Drug Reactions to Valproic Acid in Korean Epileptic Patients

The multidrug resistance protein 2 (MRP2, ABCC2) gene may determine individual susceptibility to adverse drug reactions (ADRs) in the central nervous system (CNS) by limiting brain access of antiepileptic drugs, especially valproic acid (VPA). Our objective was to investigate the effect of ABCC2 pol...

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Detalles Bibliográficos
Autores principales: Yi, Ji Hyun, Cho, Yang-Je, Kim, Won-Joo, Lee, Min Goo, Lee, Ji Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897854/
https://www.ncbi.nlm.nih.gov/pubmed/24465238
http://dx.doi.org/10.5808/GI.2013.11.4.254