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Genetic Variations of ABCC2 Gene Associated with Adverse Drug Reactions to Valproic Acid in Korean Epileptic Patients
The multidrug resistance protein 2 (MRP2, ABCC2) gene may determine individual susceptibility to adverse drug reactions (ADRs) in the central nervous system (CNS) by limiting brain access of antiepileptic drugs, especially valproic acid (VPA). Our objective was to investigate the effect of ABCC2 pol...
Autores principales: | Yi, Ji Hyun, Cho, Yang-Je, Kim, Won-Joo, Lee, Min Goo, Lee, Ji Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korea Genome Organization
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897854/ https://www.ncbi.nlm.nih.gov/pubmed/24465238 http://dx.doi.org/10.5808/GI.2013.11.4.254 |
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