IL-4 contributes to failure, and colludes with IL-10 to exacerbate Leishmania donovani infection following administration of a subcutaneous leishmanial antigen vaccine

BACKGROUND: Visceral leishmaniasis caused by the protozoan parasite Leishmania donovani complex is a potentially fatal disease if left untreated. Few treatment options exist and are toxic, costly and ineffective against resistant strains. Thus a safe and efficacious vaccine to combat this disease is...

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Detalles Bibliográficos
Autores principales: Bhowmick, Sudipta, Ravindran, Rajesh, Ali, Nahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897895/
https://www.ncbi.nlm.nih.gov/pubmed/24428931
http://dx.doi.org/10.1186/1471-2180-14-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897895/
https://www.ncbi.nlm.nih.gov/pubmed/24428931
http://dx.doi.org/10.1186/1471-2180-14-8

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