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ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7

BACKGROUND: The Sec61 channel mediates protein translocation across the endoplasmic reticulum (ER) membrane during secretory protein biogenesis, and likely also during export of misfolded proteins for ER-associated degradation (ERAD). The mechanisms of channel opening for the different modes of tran...

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Detalles Bibliográficos
Autores principales:	Tretter, Thomas, Pereira, Fábio P, Ulucan, Ozlem, Helms, Volkhard, Allan, Susanne, Kalies, Kai-Uwe, Römisch, Karin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897919/ https://www.ncbi.nlm.nih.gov/pubmed/24314051 http://dx.doi.org/10.1186/1471-2121-14-56

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