Rational selection and engineering of exogenous principal sigma factor (σ(HrdB)) to increase teicoplanin production in an industrial strain of Actinoplanes teichomyceticus

BACKGROUND: Transcriptional engineering has presented a strong ability of phenotypic improvement in microorganisms. However, it could not be directly applied to Actinoplanes teichomyceticus L-27 because of the paucity of endogenous transcription factors in the strain. In this study, exogenous transc...

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Detalles Bibliográficos
Autores principales: Wang, Haiyong, Yang, Liu, Wu, Kuo, Li, Guanghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897980/
https://www.ncbi.nlm.nih.gov/pubmed/24428890
http://dx.doi.org/10.1186/1475-2859-13-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897980/
https://www.ncbi.nlm.nih.gov/pubmed/24428890
http://dx.doi.org/10.1186/1475-2859-13-10

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