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Rational selection and engineering of exogenous principal sigma factor (σ(HrdB)) to increase teicoplanin production in an industrial strain of Actinoplanes teichomyceticus

BACKGROUND: Transcriptional engineering has presented a strong ability of phenotypic improvement in microorganisms. However, it could not be directly applied to Actinoplanes teichomyceticus L-27 because of the paucity of endogenous transcription factors in the strain. In this study, exogenous transc...

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Detalles Bibliográficos
Autores principales:	Wang, Haiyong, Yang, Liu, Wu, Kuo, Li, Guanghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897980/ https://www.ncbi.nlm.nih.gov/pubmed/24428890 http://dx.doi.org/10.1186/1475-2859-13-10

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