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Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production but fail to improve survival in experimental staphylococcal toxic shock syndrome

BACKGROUND: Toxic shock syndrome (TSS) is caused by an overwhelming host-mediated response to bacterial superantigens produced mainly by Staphylococcus aureus and Streptococcus pyogenes. TSS is characterized by aberrant activation of T cells and excessive release of pro-inflammatory cytokines ultima...

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Detalles Bibliográficos
Autores principales: Kim, Hani, Darwish, Ilyse, Monroy, Maria-Fernanda, Prockop, Darwin J, Liles, W Conrad, Kain, Kevin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898056/
https://www.ncbi.nlm.nih.gov/pubmed/24423010
http://dx.doi.org/10.1186/1471-2172-15-1