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Genome-wide Mapping of Transcriptional Start Sites Defines an Extensive Leaderless Transcriptome in Mycobacterium tuberculosis

Deciphering physiological changes that mediate transition of Mycobacterium tuberculosis between replicating and nonreplicating states is essential to understanding how the pathogen can persist in an individual host for decades. We have combined RNA sequencing (RNA-seq) of 5′ triphosphate-enriched li...

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Detalles Bibliográficos
Autores principales: Cortes, Teresa, Schubert, Olga T., Rose, Graham, Arnvig, Kristine B., Comas, Iñaki, Aebersold, Ruedi, Young, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898074/
https://www.ncbi.nlm.nih.gov/pubmed/24268774
http://dx.doi.org/10.1016/j.celrep.2013.10.031