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Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner

The phosphatidylinositol 3′ kinase (PI3K) pathway is involved in many cellular processes including cell proliferation, survival and glucose transport, and is implicated in various disease states, such as cancer and diabetes. Although there have been numerous studies dissecting the role of PI3K signa...

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Detalles Bibliográficos
Autores principales: Ling, L S, Voskas, D, Woodgett, J R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898101/
https://www.ncbi.nlm.nih.gov/pubmed/23455320
http://dx.doi.org/10.1038/onc.2013.44