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Activation of PDK-1 maintains mouse embryonic stem cell self-renewal in a PKB-dependent manner
The phosphatidylinositol 3′ kinase (PI3K) pathway is involved in many cellular processes including cell proliferation, survival and glucose transport, and is implicated in various disease states, such as cancer and diabetes. Although there have been numerous studies dissecting the role of PI3K signa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898101/ https://www.ncbi.nlm.nih.gov/pubmed/23455320 http://dx.doi.org/10.1038/onc.2013.44 |