MiR-155-mediated loss of C/EBPβ shifts the TGF-β response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer

During breast cancer progression, transforming growth factor-beta (TGF-β) switches from acting as a growth inhibitor to become a major promoter of epithelial-mesenchymal transition (EMT), invasion and metastasis. However, the mechanisms involved in this switch are not clear. We found that loss of CC...

Descripción completa

Detalles Bibliográficos
Autores principales: Johansson, J, Berg, T, Kurzejamska, E, Pang, M-F, Tabor, V, Jansson, M, Roswall, P, Pietras, K, Sund, M, Religa, P, Fuxe, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898103/
https://www.ncbi.nlm.nih.gov/pubmed/23955085
http://dx.doi.org/10.1038/onc.2013.322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898103/
https://www.ncbi.nlm.nih.gov/pubmed/23955085
http://dx.doi.org/10.1038/onc.2013.322

Ejemplares similares