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A study of genomic instability in early preneoplastic colonic lesions

It is difficult to explain the differential rates of progression of premalignant colonic lesions and differences in behaviour of morphologically similar lesions. Heterogeneity for microsatellite instability (MSI) and promoter methylation in driving these phenomena forward may explain this; however,...

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Detalles Bibliográficos
Autores principales: Beggs, A D, Domingo, E, Abulafi, M, Hodgson, S V, Tomlinson, I P M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898108/
https://www.ncbi.nlm.nih.gov/pubmed/23246972
http://dx.doi.org/10.1038/onc.2012.584