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Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R-thiomandelic acid

Metallo-β-lactamases, enzymes which inactivate β-lactam antibiotics, are of increasing biological and clinical significance as a source of antibiotic resistance in pathogenic bacteria. In the present study we describe the high-resolution solution NMR structures of the Bacillus cereus metallo-β-lacta...

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Detalles Bibliográficos
Autores principales: Karsisiotis, Andreas Ioannis, Damblon, Christian F., Roberts, Gordon C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898119/
https://www.ncbi.nlm.nih.gov/pubmed/24059435
http://dx.doi.org/10.1042/BJ20131003