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The Effects of Zileuton and Montelukast in Reperfusion-Induced Arrhythmias in Anesthetized Rats()
BACKGROUND: 5-Lipoxygenase is an enzyme involved in the synthesis of leukotriene eicosanoids from arachidonic acid. The therapeutic potential of zileuton, an inhibitor of 5-lipoxygenase, and montelukast, a cysteinyl leukotriene receptor antagonist, for the treatment of ischemia/reperfusion (I/R) inj...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898183/ https://www.ncbi.nlm.nih.gov/pubmed/24465039 http://dx.doi.org/10.1016/j.curtheres.2013.06.001 |