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The Effects of Zileuton and Montelukast in Reperfusion-Induced Arrhythmias in Anesthetized Rats()

BACKGROUND: 5-Lipoxygenase is an enzyme involved in the synthesis of leukotriene eicosanoids from arachidonic acid. The therapeutic potential of zileuton, an inhibitor of 5-lipoxygenase, and montelukast, a cysteinyl leukotriene receptor antagonist, for the treatment of ischemia/reperfusion (I/R) inj...

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Detalles Bibliográficos
Autor principal: Gonca, Ersöz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898183/
https://www.ncbi.nlm.nih.gov/pubmed/24465039
http://dx.doi.org/10.1016/j.curtheres.2013.06.001