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Crystal structures of the human Dysferlin inner DysF domain

BACKGROUND: Mutations in dysferlin, the first protein linked with the cell membrane repair mechanism, causes a group of muscular dystrophies called dysferlinopathies. Dysferlin is a type two-anchored membrane protein, with a single C terminal trans-membrane helix, and most of the protein lying in cy...

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Detalles Bibliográficos
Autores principales: Sula, Altin, Cole, Ambrose R, Yeats, Corin, Orengo, Christine, Keep, Nicholas H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898210/
https://www.ncbi.nlm.nih.gov/pubmed/24438169
http://dx.doi.org/10.1186/1472-6807-14-3