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Targeting cell cycle and hormone receptor pathways in cancer

The cyclin/cyclin-dependent kinase (CDK)/retinoblastoma (RB)-axis is a critical modulator of cell cycle entry and is aberrant in many human cancers. New nodes of therapeutic intervention are needed that can delay or combat the onset of malignancies. The antitumor properties and mechanistic functions...

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Detalles Bibliográficos
Autores principales: Comstock, C E S, Augello, M A, Goodwin, J F, de Leeuw, R, Schiewer, M J, Ostrander, W F, Burkhart, R A, McClendon, A K, McCue, P A, Trabulsi, E J, Lallas, C D, Gomella, L G, Centenera, M M, Brody, J R, Butler, L M, Tilley, W D, Knudsen, K E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898261/
https://www.ncbi.nlm.nih.gov/pubmed/23708653
http://dx.doi.org/10.1038/onc.2013.83