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Seizure-induced reduction in PIP(3) levels contributes to seizure-activity and is rescued by valproic acid()
Phosphatidylinositol (3–5) trisphosphate (PIP(3)) is a central regulator of diverse neuronal functions that are critical for seizure progression, however its role in seizures is unclear. We have recently hypothesised that valproic acid (VPA), one of the most commonly used drugs for the treatment of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898270/ https://www.ncbi.nlm.nih.gov/pubmed/24148856 http://dx.doi.org/10.1016/j.nbd.2013.10.017 |