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Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse()

Parkinson's disease (PD) is a neurodegenerative disorder classically characterized by the death of dopamine (DA) neurons in the substantia nigra pars compacta and by intracellular Lewy bodies composed largely of α-synuclein. Approximately 5–10% of PD patients have a familial form of Parkinsonis...

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Detalles Bibliográficos
Autores principales: Taylor, Tonya N., Potgieter, Dawid, Anwar, Sabina, Senior, Steven L., Janezic, Stephanie, Threlfell, Sarah, Ryan, Brent, Parkkinen, Laura, Deltheil, Thierry, Cioroch, Milena, Livieratos, Achilleas, Oliver, Peter L., Jennings, Katie A., Davies, Kay E., Ansorge, Olaf, Bannerman, David M., Cragg, Stephanie J., Wade-Martins, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898275/
https://www.ncbi.nlm.nih.gov/pubmed/24121116
http://dx.doi.org/10.1016/j.nbd.2013.10.005