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Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse()
Parkinson's disease (PD) is a neurodegenerative disorder classically characterized by the death of dopamine (DA) neurons in the substantia nigra pars compacta and by intracellular Lewy bodies composed largely of α-synuclein. Approximately 5–10% of PD patients have a familial form of Parkinsonis...
Autores principales: | Taylor, Tonya N., Potgieter, Dawid, Anwar, Sabina, Senior, Steven L., Janezic, Stephanie, Threlfell, Sarah, Ryan, Brent, Parkkinen, Laura, Deltheil, Thierry, Cioroch, Milena, Livieratos, Achilleas, Oliver, Peter L., Jennings, Katie A., Davies, Kay E., Ansorge, Olaf, Bannerman, David M., Cragg, Stephanie J., Wade-Martins, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898275/ https://www.ncbi.nlm.nih.gov/pubmed/24121116 http://dx.doi.org/10.1016/j.nbd.2013.10.005 |
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