Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein–Barr virus

Malignant cells achieve replicative immortality by two alternative mechanisms, a common one dependent on de novo synthesis of telomeric DNA by telomerase, and a rare one based on telomere recombination known as alternative lengthening of telomeres (ALT). Epstein–Barr virus (EBV) transforms human B-l...

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Detalles Bibliográficos
Autores principales: Kamranvar, S A, Chen, X, Masucci, M G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898310/
https://www.ncbi.nlm.nih.gov/pubmed/23708666
http://dx.doi.org/10.1038/onc.2013.189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898310/
https://www.ncbi.nlm.nih.gov/pubmed/23708666
http://dx.doi.org/10.1038/onc.2013.189

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