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Detection of lamivudine-resistant variants and mutations related to reduced antigenicity of HBsAg in individuals from the cities of Santos and São Paulo, Brazil

BACKGROUND: Continuous long-term treatment is recommended to reduce the hepatitis B virus (HBV) viral load. However, as a consequence, resistance mutations can emerge and be transmitted to other individuals. The polymerase (POL) gene overlaps the surface (S) gene. Thus, during treatment, mutations i...

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Detalles Bibliográficos
Autores principales: Mantovani, Nathalia, Cicero, Maira, Santana, Luiz Claudio, Silveira, Carla, do Carmo, Eliane Pereira, Abrão, Paulo Roberto Ferreira, Diaz, Ricardo Sobhie, Caseiro, Marcos Montani, Komninakis, Shirley Vasconcelos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898369/
https://www.ncbi.nlm.nih.gov/pubmed/24165277
http://dx.doi.org/10.1186/1743-422X-10-320