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Enhanced Ca(2+) influx through cardiac L-type Ca(2+) channels maintains the systolic Ca(2+) transient in early cardiac atrophy induced by mechanical unloading
Cardiac atrophy as a consequence of mechanical unloading develops following exposure to microgravity or prolonged bed rest. It also plays a central role in the reverse remodelling induced by left ventricular unloading in patients with heart failure. Surprisingly, the intracellular Ca(2+) transients...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898408/ https://www.ncbi.nlm.nih.gov/pubmed/23842739 http://dx.doi.org/10.1007/s00424-013-1316-y |