cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: Effects of PKA and EPAC()

We demonstrated that increasing intracellular cAMP concentrations result in the inhibition of migration of PANC-1 and other pancreatic ductal adenocarcinoma (PDAC) cell types. The rise of cAMP was accompanied by rapid and reversible cessation of ruffling, by inhibition of focal adhesion turnover and...

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Detalles Bibliográficos
Autores principales: Burdyga, Alex, Conant, Alan, Haynes, Lee, Zhang, Jin, Jalink, Kees, Sutton, Robert, Neoptolemos, John, Costello, Eithne, Tepikin, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898478/
https://www.ncbi.nlm.nih.gov/pubmed/23797058
http://dx.doi.org/10.1016/j.bbamcr.2013.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898478/
https://www.ncbi.nlm.nih.gov/pubmed/23797058
http://dx.doi.org/10.1016/j.bbamcr.2013.06.011

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