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FER kinase promotes breast cancer metastasis by regulating α(6)- and β(1)-integrin-dependent cell adhesion and anoikis resistance

Metastatic breast cancer cannot be treated successfully. Currently, the targeted therapies for metastatic disease are limited to human epidermal growth factor receptor 2 and hormone receptor antagonists. Understanding the mechanisms of breast cancer growth and metastasis is therefore crucial for the...

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Detalles Bibliográficos
Autores principales: Ivanova, I A, Vermeulen, J F, Ercan, C, Houthuijzen, J M, Saig, F A, Vlug, E J, van der Wall, E, van Diest, P J, Vooijs, M, Derksen, P W B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898493/
https://www.ncbi.nlm.nih.gov/pubmed/23873028
http://dx.doi.org/10.1038/onc.2013.277