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Molecular Grafting onto a Stable Framework Yields Novel Cyclic Peptides for the Treatment of Multiple Sclerosis

[Image: see text] Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) and is characterized by the destruction of myelin and axons leading to progressive disability. Peptide epitopes from CNS proteins, such as myelin oligodendrocyte glycoprotein (MOG), possess promi...

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Detalles Bibliográficos
Autores principales: Wang, Conan K., Gruber, Christian W., Cemazar, Maša, Siatskas, Christopher, Tagore, Prascilla, Payne, Natalie, Sun, Guizhi, Wang, Shunhe, Bernard, Claude C., Craik, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898541/
https://www.ncbi.nlm.nih.gov/pubmed/24147816
http://dx.doi.org/10.1021/cb400548s