Determination of key structure–activity relationships in siRNA delivery with a mixed micelle system()()

Short interfering ribonucleic acids (siRNAs) offer a highly specific and selective form of therapy for diseases with a genetic component; however the poor pharmacokinetic properties of the molecule have impeded its development into a therapeutic for use in vivo. Several different approaches have bee...

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Detalles Bibliográficos
Autores principales: Omedes Pujol, Marta, Coleman, Daniel J.L., Allen, Christopher D., Heidenreich, Olaf, Fulton, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898608/
https://www.ncbi.nlm.nih.gov/pubmed/24140749
http://dx.doi.org/10.1016/j.jconrel.2013.10.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898608/
https://www.ncbi.nlm.nih.gov/pubmed/24140749
http://dx.doi.org/10.1016/j.jconrel.2013.10.013

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