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Determination of key structure–activity relationships in siRNA delivery with a mixed micelle system()()
Short interfering ribonucleic acids (siRNAs) offer a highly specific and selective form of therapy for diseases with a genetic component; however the poor pharmacokinetic properties of the molecule have impeded its development into a therapeutic for use in vivo. Several different approaches have bee...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Publishers
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898608/ https://www.ncbi.nlm.nih.gov/pubmed/24140749 http://dx.doi.org/10.1016/j.jconrel.2013.10.013 |